Identification of Predictive and Prognostic Factors in Malignant Pleural Mesothelioma
Not Applicable
Recruiting
- Conditions
- Malignant pleural mesotheliomaCancer - Lung - Mesothelioma
- Registration Number
- ACTRN12609000839202
- Lead Sponsor
- Stephen Clarke
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Patients with a diagnosis of malignant pleural mesothelioma
- Age over 18 years.
- Ability to comply with the planned procedures and provide written evidence of informed consent.
Exclusion Criteria
- Patients with other malignancies who are undergoing active chemotherapy treatment.
- Patients with insufficient English where the QoL questionnaires are not available in their own language will be excluded only from the QoL component of the study only but can still participate in the main study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival assessed by data registry[3 years following commencement of the study]
- Secondary Outcome Measures
Name Time Method Progression Free Survival as assessed by symptoms and/or imaging modality such as CT scans on follow up[3 years after commencement of the study];Chemotherapy Response Rate as assessed by modified Response Evaluation Criteria In Solid Tumors (RECIST) criteria[after 4 cycles of chemotherapy and at completion of chemotherapy];Development of haematological and non-haematological chemotherapy toxicity as graded by National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0[after each cycles of chemotherapy]