China Cancer Foundation Beijing Hope Marathon Fund
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- Incidence of pathological regurgitation
研究概览
简要总结
The goal of this observational study intends to explore the evolution trend and related factors of postoperative reflux of esophageal cancer based on PEPTEST detection, in order to identify postoperative reflux
The main question it aims to answer are:
to provide evidence for high-risk groups, improvement of surgical methods for esophageal cancer, and development of health education programs to prevent postoperative reflux.
Using convenient sampling method, patients undergoing esophagectomy in thoracic surgery Department of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023 were continuously enrolled. PEPTEST was performed once before surgery, before discharge, 1 month, 3 months, and 6 months after surgery.
The incidence of pathological reflux at 5 time points before and after surgery was observed and compared (that is, both T-line and C-line were shown). The trend of pepsin content in saliva before and after operation; The relationship between pathological reflux and surgical factors; The relationship between pathological reflux and life habits after operation; Relationship between pathological regurgitation and demographic characteristics.
详细描述
The subjects of this study were selected from the patients who underwent esophagectomy in the Department of Thoracic Surgery of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023 to December 1, 2023, and the patients who underwent esophagectomy in the Department of thoracic surgery of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023. PEPTEST was performed once before surgery, before discharge, 1 month, 3 months, and 6 months after surgery. To describe the evolution trend of postoperative reflux in patients with esophageal cancer can be used for anticipatory sexual health education. To explore the relevant factors of reflux: to identify the inherent factors, such as gender, BMI, etc., to give preventive intervention to high-risk groups; The variable factors such as the length and width of the tube stomach can be improved.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who were pathologically diagnosed with esophageal cancer and underwent esophagectomy for esophageal cancer.
- •The patient can communicate in Mandarin.
- •Those who can come to the hospital for review on time.
排除标准
- •People with cognitive impairment or mental illness.
- •Complicating other serious life-threatening diseases (such as leukemia or autoimmune diseases).
- •Unwilling to participate in the study.
研究组 & 干预措施
3 months after surgery
Three months after surgery for esophageal cancer
干预措施: PEPTEST test (Diagnostic Test)
6 months after surgery
Six months after surgery for esophageal cancer
干预措施: PEPTEST test (Diagnostic Test)
Before surgery
A patient with esophageal cancer before surgery
干预措施: PEPTEST test (Diagnostic Test)
Before discharge
Patients with esophageal cancer who were not discharged after surgery
干预措施: PEPTEST test (Diagnostic Test)
1 month after surgery
One month after surgery for esophageal cancer
干预措施: PEPTEST test (Diagnostic Test)
结局指标
主要结局
Incidence of pathological regurgitation
时间窗: 2023.1.1-2023.12.1
Incidence of pathological regurgitation at 5 time points before and after surgery.
次要结局
未报告次要终点