China Cancer Foundation Beijing Hope Marathon Fund
概览
- 阶段
- 不适用
- 干预措施
- PEPTEST test
- 疾病 / 适应症
- GASTROINTESTINAL NEOPLASMS
- 发起方
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- 入组人数
- 138
- 试验地点
- 1
- 主要终点
- Incidence of pathological regurgitation
- 状态
- Enrolling By Invitation
- 最后更新
- 26天前
概览
简要总结
The goal of this observational study intends to explore the evolution trend and related factors of postoperative reflux of esophageal cancer based on PEPTEST detection, in order to identify postoperative reflux
The main question it aims to answer are:
to provide evidence for high-risk groups, improvement of surgical methods for esophageal cancer, and development of health education programs to prevent postoperative reflux.
Using convenient sampling method, patients undergoing esophagectomy in thoracic surgery Department of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023 were continuously enrolled. PEPTEST was performed once before surgery, before discharge, 1 month, 3 months, and 6 months after surgery.
The incidence of pathological reflux at 5 time points before and after surgery was observed and compared (that is, both T-line and C-line were shown). The trend of pepsin content in saliva before and after operation; The relationship between pathological reflux and surgical factors; The relationship between pathological reflux and life habits after operation; Relationship between pathological regurgitation and demographic characteristics.
详细描述
The subjects of this study were selected from the patients who underwent esophagectomy in the Department of Thoracic Surgery of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023 to December 1, 2023, and the patients who underwent esophagectomy in the Department of thoracic surgery of Cancer Hospital of Chinese Academy of Medical Sciences from January 1, 2023. PEPTEST was performed once before surgery, before discharge, 1 month, 3 months, and 6 months after surgery. To describe the evolution trend of postoperative reflux in patients with esophageal cancer can be used for anticipatory sexual health education. To explore the relevant factors of reflux: to identify the inherent factors, such as gender, BMI, etc., to give preventive intervention to high-risk groups; The variable factors such as the length and width of the tube stomach can be improved.
研究者
入排标准
入选标准
- •Patients who were pathologically diagnosed with esophageal cancer and underwent esophagectomy for esophageal cancer.
- •The patient can communicate in Mandarin.
- •Those who can come to the hospital for review on time.
排除标准
- •People with cognitive impairment or mental illness.
- •Complicating other serious life-threatening diseases (such as leukemia or autoimmune diseases).
- •Unwilling to participate in the study.
研究组 & 干预措施
3 months after surgery
Three months after surgery for esophageal cancer
干预措施: PEPTEST test
6 months after surgery
Six months after surgery for esophageal cancer
干预措施: PEPTEST test
Before surgery
A patient with esophageal cancer before surgery
干预措施: PEPTEST test
Before discharge
Patients with esophageal cancer who were not discharged after surgery
干预措施: PEPTEST test
1 month after surgery
One month after surgery for esophageal cancer
干预措施: PEPTEST test
结局指标
主要结局
Incidence of pathological regurgitation
时间窗: 2023.1.1-2023.12.1
Incidence of pathological regurgitation at 5 time points before and after surgery.