Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 556
- 主要终点
- Between-groups difference in the estimated reduction of mortality due to lung cancer screening
研究概览
简要总结
This study evaluates whether doctors are familiar with the statistical background of lung cancer screening.
详细描述
Background: Screening with low-dose CT scan can prevent three deaths due to lung cancer among 1000 high-risk individuals. However, false-positive results and radiation exposure are relevant disadvantages deserving accurate consideration. Candidates for screening can only make an autonomous decision if doctors inform them correctly about the pros and cons of the method. Therefore, this study aims to evaluate, whether doctors understand the test characteristics of lung cancer screening.
Methods: In a randomized trial, 556 doctors (members of the Austrian Respiratory Society) will be invited to answer questions regarding lung cancer screening based on online case vignettes. Half of the participants will be randomized to the group 'with data' and will receive the correct solutions in advance. The group 'without data' will have to rely on prior knowledge or estimate. Primary endpoint will be the between-groups difference in the estimated number of deaths preventable by screening. Secondary endpoints will be the between-groups differences in prevalence of lung cancer, prevalence of suspicious results, sensitivity, specificity, positive-predictive value, and false negative rate. Estimations will also be compared to actual values from the literature.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Doctors, who were in training or had a completed specialization training in:
- •Pneumonology
- •Internal Medicine
- •or Radiology
排除标准
- •Doctors, with a specialized training in
- •Pediatrics
- •Pathology and doctors who had no e-mail address were excluded.
研究组 & 干预措施
With Data
Participants received statistical data about lung cancer screening
干预措施: With Data (Other)
Without Data
Participants had no statistical data on lung cancer screening
结局指标
主要结局
Between-groups difference in the estimated reduction of mortality due to lung cancer screening
时间窗: 14 days
Participants had 14 days to complete the survey
次要结局
- Between-groups difference prevalence of lung cancer(14 days)
- Between-groups difference in sensitivity of lung cancer screening(14 days)
- Between-groups difference in the frequency of a positive test result(14 days)
- Between-groups difference in specificity of lung cancer screening(14 days)
- Between-groups difference in positive predictive value of lung cancer screening(14 days)
- Between-groups difference in the false negative rate of lung cancer screening(14 days)
研究者
Georg-Christian Funk
Priv. Doz. Dr.
Otto Wagner Hospital