Efficacy of Aparajita Arka in Galaganda with special reference to Hypothyroidism A Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To evaluate the Efficacy of Aparajita Arka in the management of Galaganda Chikitsa wsr to Hypothyroidism
研究概览
简要总结
Hypothyroidism is believed to be a common health issue in India as it is present worldwide. The prevalence of hypothyroidism was high, affecting approximately one in 10 adults in the study population. Female gender and older age were found to have significant association with hypothyroidismand clinical manifestations of hypothyroidism range from life threatening to no signs or symptoms. The most common symptoms in adults are fatigue, lethargy, cold intolerance, weight gain, constipation, change in voice, and dry skin, but clinical presentation can differ with age and sex. According to Charaka presentation of multiple Granthi around the neck is called Gandamala and single swelling on the Parshva of the neck is Galaganda.
Review of literature
The most common cause of hypothyroidism is the inability of the thyroid gland to produce a sufficient amount of thyroid hormone however less commonly pituitary and hypothalamus impairment may also result in thyroid dysfunction. The hypothalamus secretes thyrotropin releasing hormone (TRH) that stimulates the pituitary gland to produce thyroid-stimulating hormone (TSH). Thyroid-stimulating hormones stimulate the thyroid gland to produce and secrete mainly T4, approximately 77 to 155 nmol/L, and smaller quantities of T3 of 1.2-2.8 nmol/L.
AIM: Effect of Aparajita Arka in the management of Galaganda Chikitsa w.s.r to Hypothyroidism
OBJECTIVE OF THE STUDY:
Primary Objective :
To evaluate the Efficacy of Aparajita Arka in the management of Galaganda Chikitsa w.s.r to Hypothyroidism.
Secondary Objective :
To Compare the effect of Aparajita Arka with Kanchanara Guggulu in the management of Galaganda chikitsa w.s.r to Hypothyroidism .
**HYPOTHESIS:**H0: Aparajita Arka is not comparable to Kanchanar guggulu in the management of Galaganda w.s.r to Hypothyroidism .
H1: Aparajita Arka is comparable to Kanchanar guggulu in the management of Galaganda w.s.r to Hypothyroidism.
RESEARCH QUESTION:
Whether the Aparajita Arka is effective in the management Galaganda w. s. r to Hypothyroidism intake daily for a period of 30 days?
EXPECTED OUTCOME:
May help in the reduction of signs and symptoms
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with TSH level of greater than 4.5 ml U per L AACE but below 20ml U per L.
排除标准
- •TSH level more than 20ml U per L Pregnant women goiter associated with metastasis condition Patient under Hypothyroidism medication.
结局指标
主要结局
To evaluate the Efficacy of Aparajita Arka in the management of Galaganda Chikitsa wsr to Hypothyroidism
时间窗: 30 Days of intervention and followup
次要结局
- To Compare the effect of Aparajita Arka with Kanchanara Guggulu in the management of Galaganda chikitsa wsr to Hypothyroidism(30 Days of intervention and followup)
研究者
Dr Sushree Saswati Nayak
KAHERs Shri BMK Ayurveda Mahavidyalaya