Abnormalities of thrombotic factor in children and adolescents hospitalized with a relapse of nephrotic syndrome
Not Applicable
- Conditions
- Health Condition 1: N049- Nephrotic syndrome with unspecified morphologic changes
- Registration Number
- CTRI/2024/07/071421
- Lead Sponsor
- Department of Pediatrics Maulana Azad Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children and adolescents hospitalized with a relapse of nephrotic syndrome
Exclusion Criteria
1. Presence of concomitant acute hepatitis/ liver disease
2. Already on anticoagulants
3. Patients admitted for renal biopsy
4. Congenital nephrotic syndrome
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients with altered levels of antithrombin III, Protein C, Protein STimepoint: At admission and at discharge /2 weeks of hospitalization whichever is earlier
- Secondary Outcome Measures
Name Time Method Association of Prothrombotic factors with disease type, duration, therapy, presence of infection and hypovolemiaTimepoint: At admission and at discharge /2 weeks of hospitalization whichever is earlier;Proportion of patients with altered coagulation profile parameters (PT/INR/aPTT/Platelet count)Timepoint: At admission and at discharge /2 weeks of hospitalization whichever is earlier;Proportion of patients with altered D-Dimer, Fibrinogen and FDPTimepoint: At admission and at discharge /2 weeks of hospitalization whichever is earlier;Proportion of patients with presence of Factor V Leiden mutationTimepoint: At admission and at discharge /2 weeks of hospitalization whichever is earlier