Labial Biopsy in Patients With Tuberculosis Disease

Completed

• Conditions: Sarcoidosis; Tuberculosis
• Interventions: Other: labial biopsy

• Registration Number: NCT02115854
• Lead Sponsor: Hopital Lariboisière

Brief Summary

The distinction between Tuberculosis disease (TB), a worldwide infective granulomatosis requiring long-term antibiotic treatment, and sarcoïdosis, a rare granulomatous disease successfully treated with high dose steroids is not straightforward and may delay the treatment choice by the physician.

The goal was to evaluate prospectively and consecutively the presence of epithelioid granulomas in salivary glands biopsy of patients with TB.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Status Verified: 2014-04
• Primary Completion: 2014-04
• Study First Submitted: 2014-04-10
• Study First Submitted QC: 2014-04-15
• Last Update Submitted: 2014-04-15
• Study First Posted: 2014-04-16
• Last Update Posted: 2014-04-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• adults above 18 years,
• bacteriologically confirmed tuberculosis

Exclusion Criteria

• patient not able to sign written consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
bacteriologically confirmed tuberculosis	labial biopsy	-

Primary Outcome Measures

Name	Time	Method
presence of granuloma on labial biopsy	at day zero of treatment of tuberculosis

Trial Locations

Locations (1)

Unite de Recherche Thérapeutique; 🇫🇷 Paris, France