Medicated Thread in The Management Of Bhagandara (Fistula -In-Ano)

Phase 2

Not yet recruiting

• Conditions: Disease of digestive system, unspecified,

• Registration Number: CTRI/2020/05/025140
• Lead Sponsor: National institute of Ayurveda

Brief Summary

*Ksharasutra* isroutinely prepared with *Snuhi Kshira*, *Apamarga Kshara* and *HaridraChurna*. It is known as standard *Apamarga Ksharasutra* and is knowndevice for the treatment of Fistula-in-ano and has been standardized by theDepartment of *Shalya*/*Shalakya*, Banaras Hindu University, Varanasiand the CCRAS. Since we cannot depend always on single type of *Ksharasutra*and there is a need to explore other drugs which can be used in the preparationof *Ksharasutra* in accordance with the references made by our *Acharyas*at different places in their treatises.

India is a vast country with variedflora so there is a need to search for an alternate plants which can play abetter role in the preparation of *Ksharasutra* in terms of efficacy. *Snuhi*can be a better alternative if proved efficient in the proposed study which hasa special mention in the *Sushruta Samhita* becauseno studies havebeen carried out on this drug in the management of *Bhagandara,* thereforethere is a need to evaluate its efficacy.

*Acharya Sushruta*has mentioned in the *Sushruta Samhita Sutra Sthana* chapter 11 verse 12 (*Ksharapakavidhiadhyaya*)about the *Snuhi* as one of the plants which can be used in thepreparation of *Kshara* which is *Tikshna Virechana, lekhna, Shoolhar,Shothahar*, *Raktashodhana* And *Stambhana.* *Snuhi* isabundantly and easily available and its preservation for longer periods iseasier.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-04-27
• Study Start: 2020-05-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 1.Male or female between age 18 to 60 years and willing to give their written Informed consent.
• 2.No major systemic disease involved.
• Patients who have signs and symptoms of Bhagandara (fistula-in-ano).

Exclusion Criteria

• 1.Male or female less than 18 years and greater than 60 years of age.
• 2.Patient with known hypersensitivity to any of the components of the formulation.
• Bhagandara (Fistula-in-ano) associated with one or more of the following conditions:- A.
• Ulcerative Colitis B.
• Uncontrolled Hypertension C.
• Uncontrolled Diabetes Mellitus D.
• Veneral diseases E.
• HIV and Hepatitis B,C patients F.
• Crohn’s disease G.
• Fistula other than ano-rectal area.
• Supra Levator Fistula.
• J.CA Rectum.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of Snuhi Ksharasutra with standard Apamarga Ksharasutra in the management of Bhagandara.	12 Weeks

Secondary Outcome Measures

Name	Time	Method
To evaluate the efficacy of Snuhi Ksharasutra in the management of Bhagandara.	To perform Phytochemical analysis of prepared Snuhi Kshara

Trial Locations

Locations (1)

National Institute of Ayurveda, Jaipur.; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of Ayurveda, Jaipur.

🇮🇳Jaipur, RAJASTHAN, India

Dr Rohitash Gurjar

Principal investigator

9785414287

rohitgurjar080@gmail.com