Ultrasound Measurement of Optic Nerve Sheath Diameter as Non-Invasive Detector of Raised Intracranial Pressure in Adult Traumatic and Non-Traumatic Neurocritical Patients in ICU

Completed

• Conditions: Ultrasound; Optic Nerve Sheath Diameter; Non-Invasive; Intracranial Pressure; Neurocritical; Intensive Care Unit

• Registration Number: NCT06993961
• Lead Sponsor: Ain Shams University

Brief Summary

This study aimed to assess the role of ultrasound as a non-invasive method (bedside) to measure the rise of intracranial pressure by measuring the optic nerve sheath diameter in traumatic and nontraumatic neurocritical patients.

Detailed Description

Measurement of intracranial pressure (ICP) is crucial in the management of many neurological conditions. However, due to the invasiveness, high cost, and required expertise of available ICP monitoring techniques, many patients who could benefit from it do not receive it. As a result, a substantial effort has been made to explore and develop novel non-invasive ICP monitoring techniques to improve the overall clinical care of patients suffering from ICP disorders.

Study Timeline

• Study Start: 2022-08-01
• Primary Completion: 2023-07-01
• Study Completion: 2023-07-01
• Status Verified: 2025-05
• Study First Submitted: 2025-05-20
• Study First Submitted QC: 2025-05-20
• Last Update Submitted: 2025-05-20
• Study First Posted: 2025-05-29
• Last Update Posted: 2025-05-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age >18 years old.
• Both sexes.
• Patients with suspected high intracranial pressure.

Exclusion Criteria

• Cases suffering from eye disease or optic nerve problems (Glaucoma, optic Nerve Tumor, Neuritis, Orbital Fracture).
• Patients suffering from mental illness render them incapable of communication & cooperation (For Example: Dementia and irritability).
• Any previous intensive care surgeries & hyperthyroidism (due to exophthalmos)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intracranial Pressure	24 hours post-procedure	Non-invasive bedside intracranial pressure (ICP) assessment via ultrasound (US) measurement of optic nerve sheath diameter (ONSD).

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt