Consumption of Probiotics on Salivary Bacteria Causing Dental Caries
- Conditions
- Dental Caries
- Registration Number
- NCT02752594
- Lead Sponsor
- Sharda University
- Brief Summary
Dental caries is a multifactorial disease effecting majority of the human population.One of the etiological factor causing dental caries is salivary mutans streptococci. Reducing the levels of this bacteria in the saliva can significantly reduce the incidence of dental caries. A non-invasive intervention, such as the administration of probiotics reduced the salivary mutans streptococci levels.
- Detailed Description
40 candidates were selected from a pre-determined group and were randomly assigned to two groups. Group A (n=20) was administered probiotic drink and Group B (n=20) was administered placebo for 14 consecutive days. Saliva was collected on day 1 and day 15 to compare the salivary mutans streptococci levels.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Decayed Missing Filled Surfaces less than or equal to 6
- Brushes twice daily
- undergoing orthodontic treatment
- topical fluoride therapy in the past 2 yrs
- using sugar free gums
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method counts of streptococcus mutans after the consumption of probiotic 15 days Human saliva was assessed for the counts of streptococcus mutans, one of the major etiological factor for dental caries
- Secondary Outcome Measures
Name Time Method