Prospective Validation of the Prognostic Value of Long Non-coding MFI2-AS1 RNA in Localized Clear Cell Kidney Cancers
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 260
- 试验地点
- 1
- 主要终点
- Expression of MFI2-AS1
研究概览
简要总结
An exploratory analysis of the expression of MFI2-AS1 will be performed at the plasma level with the objective of comparing this expression with tumor tissue. The objective would be to be able to use long non-coding RNA as a biomarker for diagnosis before tissue analysis and for patient follow-up. In addition, correlations will be made between tumor expression of MFI2-AS1 and genetic and immune alterations in tumors in order to better clarify the link between the expression of this long non-coding RNA and the characteristics of the tumor and of the tumor. tumor microenvironment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patient
- •Localized kidney tumors> T1a
- •Patient having signed an informed consent
- •Patient affiliated to a health insurance plan
- •Subject having signed a consent form to participate in research and the constitution of a collection and genetic analyzes
排除标准
- •Metastatic carcinoma from the outset
- •Contraindication to performing a TAP CT with injection of contrast product
- •Inability to provide informed information about the subject (subject in an emergency situation, difficulties in understanding, etc.)
- •Subject under legal protection
- •Subject under tutorship or curatorship
- •Pregnancy
- •Feeding with milk
结局指标
主要结局
Expression of MFI2-AS1
时间窗: 36 month
To assess the link between tumor expression of MFI2-AS1 in patients with localized clear cell kidney carcinoma and the occurrence of relapse
次要结局
未报告次要终点