EUCTR2014-003589-25-SEActive, not recruitingNot Applicable
The effect of levosimendan, on renal blood flow, function and oxygen uptake during acute renal failure after cardiac surgery - Levo-AKI
Conditions
Drugs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •-Patient to undergo a planned heart surgery with heart-lung machine
- •-Patient must have normal renal function preoperatively, s-creatinine <110 umol/L
- •-Age > 18 years
- •-Patient must have developed acute renal failure, defined as serum creatinine increase> 50% or 27 mmol / L
- •-Patient and/or family members must be in favor of participating in the investigation
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 25
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 5
Exclusion Criteria
- •-Ongoing treatment with inotropes such as milrinone, levosimendan, dopamine or dobutamine (norepinephrine does not count as inotropic drugs)
- •-Second central venous saturation <60% despite optimization of volume status and hematocrit
- •-Pregnant women in the first trimester due 51 Cr-EDTA (radiolabeled)
- •-Pregnant women due lack of documentation of levosimendan
Investigators
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