Effects of Different Intra-arterial Catheter Size on Frequency of Optimal Dynamic Response in Radial Arterial Waveform

Not Applicable

• Conditions: Catheters
• Interventions: Device: different intra-arterial catheter size

• Registration Number: NCT03642756
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The aim of this study is to compare the effects of different intra-arterial catheter size on the frequency of optimal dynamic response in radial arterial waveform.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-07-27
• Status Verified: 2018-08
• Study First Submitted QC: 2018-08-21
• Last Update Submitted: 2018-08-21
• Study First Posted: 2018-08-22
• Last Update Posted: 2018-08-22
• Study Start: 2018-10-01
• Primary Completion: 2019-10-01
• Study Completion: 2019-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 366

Inclusion Criteria

• patients who were scheduled for elective neurosurgery under general anesthesia
• patients with age of 20-79 and ASA class I-III
• patients who are needed to establish invasive arterial pressure monitoring

Exclusion Criteria

• patients who refuted to be involved in the study
• patients with age of <20 or >80
• patients who had both arm saved
• patients who had a previous history of surgery on radial artery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
22 gauge	different intra-arterial catheter size	-
24 gauge	different intra-arterial catheter size	-
20 gauge	different intra-arterial catheter size	-

Primary Outcome Measures

Name	Time	Method
The frequency of adequately damped arterial waveform	1 minute after cannulation	The accuracy of arterial blood pressure waveform is depedent on damping coefficient (DC) and natural frequency (NF). The extent to which a monitoring system is damped is expressed by the DC, while the frequency of oscillation that a monitoring system resonates at is known as the NF. The NF and DC are required to be within certain rages for accurate blood pressure monitoring, and they can be affected by different arterial catheter size. Adequately damped arterial waveform can be defined as NF and DC being within certain ranges. For example, waveforms with DC of 0.5 at a NF of 15Hz can be regarded as adequately damped arterial waveform. However, if waveforms have DC of 0.1 at a NF of 15Hz, these can be regarded as not having optimal dynamic response. (There is a reference figure explaining these factors in detail in a previous article. Gardner RM: Direct blood pressure measurement--dynamic response requirements. Anesthesiology 1981; 54:227-3)

Secondary Outcome Measures

Name	Time	Method
The difference of mean blood pressure between invasive blood pressure and non-invasive blood pressure	1 minute after cannulation	At 1 minute after cannulating radial artery, we will obtain information about the mean blood pressure measured in both invasive blood pressure and non-invasive blood pressure. Invasive blood pressure will be measured from radial artery cannulation, and non-invasive blood pressure will be measured by blood pressure cuff at Rt. upper arm. Thereafter, the difference of mean blood pressure between two values will be used for data analysis.

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of