Barrier Measures to Limit Covid-19.Nosocomial Transmission: a Cross-sectional Evaluation

• Conditions: Caregivers; COVID-19
• Interventions: Other: Survey

• Registration Number: NCT04376944
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Use lay language. The Covid-19 pandemic hit France in March 2020 and stage 3 of the epidemic justified the introduction of national and unprecedented containment measures from March 17, 2020. The Montpellier CHU experienced peak hospitalizations of Covid-19 infections in late March. The estimate of the proportion of infected people in Occitania, South of France, for the 11th of May 2020 is 3.1% (95% CI: 1.9-5.9) for the Occitania region, to which Montpellier belongs.

In the context of the Covid-19 epidemic, notably due to the absence of pharmacological or vaccine prophylaxis, barrier measures were of crucial importance, especially for exposed caregivers. These measures include an adaptation of individual behavior, the creation of a so-called "Covid" hospital, the wearing of specific equipment in all departments, the use in the rooms of Covid-19 patients of a gown, an apron, gloves, and a FFP2 type mask in the event of contact and sampling, protocolized and standardized bio-cleaning measures, a reorganization of the premises and the definition of specific circuits.

In view of the second wave of the epidemic, estimating the effectiveness of the barrier measures is of major importance. The investigators therefore propose an evaluation of the effectiveness of these measures, by comparing the serological prevalence of infection among caregivers working directly in COVID units compared to caregivers working in services excluding the management of Covid-19 patients.

Systematic evaluation in COVID-19 units of Sarc-Co-V2 infection will also be assessed, with naso-pharyngeal swabs.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-01
• Status Verified: 2020-05
• Study First Submitted: 2020-05-04
• Study First Submitted QC: 2020-05-05
• Last Update Submitted: 2020-05-05
• Study First Posted: 2020-05-06
• Last Update Posted: 2020-05-06
• Primary Completion: 2020-12-01
• Study Completion: 2020-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Exposed group	Survey	Caregivers and agents working directly in COVID units compared to those living.
Control group	Survey	caregivers anf agents working in services excluding the management of patients screened positive for Covid-19 infection

Primary Outcome Measures

Name	Time	Method
Proportion of caregivers and agents with a positive serodiagnosis	1 day	Proportion of caregivers and agents with a positive serodiagnosis in COVID units versus non-COVID units

Secondary Outcome Measures

Name	Time	Method
Proportion of caregivers and agents with a positive RT-PCR	1 day	Proportion of caregivers and agents with a positive RT-PCR in COVID units versus non-COVID units

Trial Locations

Locations (1)

Uh Montpellier; 🇫🇷 Montpellier, France