the effect of hyperbaric oxygen therapy on immune response and oxidative stress

Completed

• Conditions: Immuun response and reactive oxygen species; inflammation & oxidative stress; 10003816; 10004018; 10017998

• Registration Number: NL-OMON48412
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

- Male
- Healthy
- Age 18-40
- Be able to read and understand Dutch

Exclusion Criteria

- Language barrier
- Unable to give informed consent
- Unfit for hyperbaric oxygen therapy as assessed by the hyperbaric physician

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Immunologic effects defined by neutrophil intracellular ROS generation,<br /><br>phagocytosis assays, plasma cytokine concentrations, HLA-DRA mRNA expression,<br /><br>malondialdehyde concentration and ex vivo whole blood stimulation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>