Comparison of CE-MRI and CEUS for Measuring Tumor Size of HCC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 194
- 试验地点
- 1
- 主要终点
- measuring HCC diameter
研究概览
简要总结
Knowing the tumor size before operation is of great significance to the choice of treatment methods of surgeons and the prognosis of patients. In this study, two commonly used imaging methods( CE-MRI/CEUS) were selected to measure and compare the tumor size before operation, in order to determine which measurement method is more accurate.
详细描述
A total of 194 patients who met the inclusion criteria from January 2019 through May 2024 were included. Taken pathological results as the gold standard, Paired T-test and Bland-Altman analisis were conducted to assess the correlation and mean absolute error between the measured tumor sizes obtained from CE-MRI/CEUS and pathological results.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •had no anti-HCC therapy before imaging examinations.
- •at least had one examination of Gd-EOB-DTPA-enhanced MRI and CEUS 2 weeks before surgery and confirmed as one single HCC.
- •If the patient had both imaging tests, the time interval between two examinations was less than 1 weeks.
- •both radiological and pathological results recorded the maximum tumor diameter.
排除标准
- •had anti-HCC therapy before imaging examinations.
- •had no examination of Gd-EOB-DTPA-enhanced MRI or CEUS 2 weeks before surgery .
- •had no radiological or pathological results recorded the maximum tumor diameter.
结局指标
主要结局
measuring HCC diameter
时间窗: Jaunary 2019 - May 2024
the performance of Gd-EOB-DTPA-enhanced MRI (CE-MRI) and Contrast-enhanced Ultrasound (CEUS) in measuring tumor size of solitary hepatocellular carcinoma (HCC) ≤5cm.
次要结局
未报告次要终点
研究者
Kunyuan Jiang
Anhui Medical University
Anhui Medical University