Does the perioperative use of Gabapentin reduce analgesia requirements in patients having delayed open reduction and internal fixation of forearm or ankle fractures?

Phase 2

• Conditions: Peri-operative pain; Forearm and ankle fractures; Anaesthesiology - Pain management; Injuries and Accidents - Fractures

• Registration Number: ACTRN12610000848000
• Lead Sponsor: Iain Salkield

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Have to have a fracture of the wrist or ankle that is to be treated by internal fixation and be able to understand how to use a PCA device.

Exclusion Criteria

Pregnancy, Non-adult patients due to the hospital being non-paediatric, any patient unable to use PCA.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total dose of fentanyl used over period of study - intra-operatively and via Patient Controlled Analgesia (PCA) device[After 24 hours use of PCA, started immediately after surgery.]

Secondary Outcome Measures

Name	Time	Method
ausea/Vomiting using a score of 0-3[At any time following the administration of the initial dose of gabapentin until up to 24 hours of subsequent gabapentin use.];Dizziness Yes/No[At any time following the administration of the initial dose of gabapentin until up to 24 hours of subsequent gabapentin use.];Sedation (using a score combining sedation (0-2) and rousability(Yes/No))[At any time following the administration of the initial dose of gabapentin until up to 24 hours of subsequent gabapentin use.]