A randomised, cross-over, pilot trial investigating the effects of a novel renal dietary intervention (rich in plant foods, utilising a whole food dietary approach) designed to improve diet quality, symptom burden, the gastrointestinal microbiome and other health outcomes including biochemical markers in adults with moderate to severe chronic kidney disease.

niversity of Wollongong0 个研究点目标入组 28 人开始时间: 2019年3月18日最近更新: 2023年1月9日

适应症

试验速览

暂无简介。

•Participants diagnosed with stage 3-4 CKD non-dialysing/ pre-dialysis (eGFR 15-59mL/min per 1.73m2) or individuals deemed suitable by the medical team (Nephrologist).
•- Adults (aged 18 years old or more)
•- Participants must be able to give informed consent; i.e. have no major cognitive or sensory impairment

•Individuals who are less than 18 years of age
•Individuals with intellectual or mental impairment as well as those with a hearing impairment will only be excluded if they cannot follow safety simple instructions due to concerns relevant to the safety of the patient.
•Individuals receiving dialysis
•Individuals diagnosed with dysphagia and/or require texture modified diet
•Any women who are found to be pregnant during the trial would need to be immediately excluded due to the increased medical demands of a pregnancy in kidney disease.
•Individuals with past or present radiation to the bowel or large bowel resection
•Individuals with advanced colorectal cancer
•Individuals who consumed antibiotic therapy within 1 months of study commencement
•Individuals with medically diagnosed irritable bowel syndrome, crohn’s disease or ulcerative colitis;
•Individuals who have had a clinically significant change to their immunosuppressant dose within the last 6 months (determined by the medical team) of study commencement.

发起方

niversity of Wollongong