Mie elective Caesarean section Anesthesia trial (MCA trial)
- Conditions
- hypotension
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 70
- Age 18 years or older
- Elective cesarean section after 37 weeks of pregnancy
- Singleton pregnancy
- Written consent has been obtained from the patient
Patients with hypertension systolic blood pressure over140 mmHg or diastolic blood pressure over90 mmHg) at the time of registration Patients with cardiac, vascular, renal, or coagulation disorders Patients with pregnancy-related complications, hypertension, gestational hypertension, chronic kidney disease, etc. Those with either amniotic fluid abnormalities or fetal growth retardation Those with fetal malformations that affect umbilical artery blood gas analysis and neonatal respiratory support after birth Those with drug allergy to phenylephrine hydrochloride Those who are judged by the principal investigator/associate investigator to be inappropriate as subjects for this clinical trial
Study & Design
- Study Type
- Interventional
- Study Design
- parallel assignment
- Primary Outcome Measures
Name Time Method Maternal blood pressure variability from spinal anesthesia to delivery of the infant Maternal blood pressure variability from spinal anesthesia to delivery of the infant
- Secondary Outcome Measures
Name Time Method Group differences in maternal and neonatal background maternal-related information, age, delivery week, complications, height, pre-pregnancy weight, weight at delivery, number of births, neonatal-related information, sex, APGAR Score, 1 min value 5 min value, height, weight
Blood pressure related parameters Number of occurrence of hypotension measured by brachial manchette, maximum systolic blood pressure, minimum systolic blood pressure, maximum diastolic blood pressure, minimum systolic blood pressure, maternal blood pressure changes during the observation period
maximum systolic blood pressure manus minimum systolic blood pressure, maximum diastolic blood pressure mainus minimum diastolic blood pressureOccurrence of hypotension measured by CLEARSIGHT maximum systolic blood pressure, minimum systolic blood pressure, maximum diastolic blood pressure, minimum systolic blood pressure, course of maternal cardiac output, and changes in maternal blood pressure during the observation period
maximum systolic blood pressure mainus minimum systolic blood pressure
maximum diastolic blood pressure mainus minimum diastolic blood pressureNeonatal effects: umbilical cord blood gas analysis pH, Base Ecess, pCO2, pO2, neonatal blood glucose,after birth,
Neonatal blood glucose,from blood tests in the NICU after birth, frequency of neonatal respiratory support needs,for respiratory support required after postnatal resuscitation, NICU admission, and NICU admission.
initial blood test findings after admission to the NICU, blood gas analysis,Total dose of phenylephrine hydrochloride, mg from the start of lumbar anesthesia to the delivery of the infant, and from the start of lumbar anesthesia to the end of surgery