IRCT20240115060698N1
Recruiting
Phase 3
The assessment of probiotics' effects on gastrointestinal inflammation and symptoms in patients with scleroderma
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Scleroderma.
- Sponsor
- Mashhad University of Medical Sciences
- Enrollment
- 44
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of scleroderma based on ACR\-Eular criteria
- •Patients aged 20 to 65 years
- •Scleroderma patients with malabsorption symptoms such as bloating, bowel dysfunction, cyclic constipation and diarrhea, heartburn
- •If taking corticosteroids, they have not changed the dose of corticosteroids in the past month.
Exclusion Criteria
- •Breastfeeding
- •Active infection
- •New organ involvement
- •Irritable bowel disease
- •Inflammatory bowel disease (IBD) and ulcerative colitis (UC)
- •Antibiotic intake in past 2 weeks
- •Probiotic intake in past 4 weeks
- •Endoxan in past 4 weeks
- •Rituximab in past 4 weeks
- •Biologic drugs in past 4 weeks
Outcomes
Primary Outcomes
Not specified
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