Studying the Relationship Between Contact Lens Packaging Solutions and Bacterial Binding to Surface Eye Cells
Not Applicable
Withdrawn
- Conditions
- Corneal Ulcer
- Registration Number
- NCT01104961
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Brief Summary
The goal of this study is to investigate the overall theory that the use of chemically preserved solutions associated with contact lenses promotes an increase in bacterial infection.
- Detailed Description
The purpose of this study is to investigate the theory of bacterial binding to surface eye cells through the use of chemically preserved solutions.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Age range: 18-38 years
- Any sex, race or national origin accepted as with our past studies. Minority representation will be proactively encouraged.
- No prior history of any contact lens wear within one month of entry into the study.
- No history of allergic eye disease either seasonal or associated with previous contact lens wear.
Exclusion Criteria
- Any patient that is a current contact lens wearer.
- Patients with active ocular infection or inflammatory disease, history of herpetic keratitis, glaucoma, etc.
- Uncontrolled systemic disease or the presence of any significant illness or condition that could, in the judgment of the investigator, interfere with interpretation of the study results.
- Any patient using ocular tears, anti-histamine based ocular therapies, glaucoma therapy, vasoconstricting drops, etc.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Bacterial binding of Pseudomonas Aeruginosa 5 weeks Counting the number of bacteria that bind to surface epithelial cells.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UT Southwestern Medical Center
🇺🇸Dallas, Texas, United States
UT Southwestern Medical Center🇺🇸Dallas, Texas, United States