NCT01115959已完成4 期
Are Post Intracerebal Hemorrhage Prevented By Anti-Epileptic Treatment?
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 72
- 主要终点
- number of seizures
研究概览
简要总结
This study examines early antiepileptic treatment with valproic acid for acute cerebral hemorrhage against a placebo group immediately post event to evaluate the outcome of these patients regarding seizures and neurological outcome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cerebral hemorrhage spontaneous
排除标准
- •early seizures
研究组 & 干预措施
valproic acid
Active Comparator
Valproic acid given orally 400mg twice daily
干预措施: valproic acid (Drug)
valproic acid
Active Comparator
Valproic acid given orally 400mg twice daily
干预措施: placebo bid (Drug)
placebo
Placebo Comparator
Placebo twice daily for one month
干预措施: placebo bid (Drug)
结局指标
主要结局
number of seizures
时间窗: study drug for 1 month and 1 year follow up
次要结局
- neurological outcome NIHSS(during 1 month study drug and 1 year post follow up)
研究者
Dr. Yair Lampl
Professor Yair Lampl
Wolfson Medical Center
相似试验
招募中
4 期
Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis (HITs)Antiplatelet TherapyHemorrhagic InfarctionNCT04624295Second Affiliated Hospital, School of Medicine, Zhejiang University294
Unknown
1 期
Traumatic Neuroprotection and Epilepsy Prevention of Valproate AcidTraumatic Brain InjuryNCT02027987Xijing Hospital160
已完成
不适用
The Effect of Anti-epileptic Drugs on Mitochondrial ActivityEpilepsyNCT01218321Hadassah Medical Organization60
Unknown
不适用
Cerebral Microbleeds During NOACs or Warfarin Therapy in NVAF Patients With Acute Ischemic Stroke (CMB-NOW)Ischemic StrokeAtrial Fibrillation SymptomaticNCT02356432Tokai University86
已完成
2 期
Anti-epileptogenic Effects of Eslicarbazepine AcetatePost Stroke EpilepsyNCT06597084Bial - Portela C S.A.129