EUCTR2006-002667-33-BE
Active, not recruiting
Not Applicable
Phase I/II study on induction chemotherapy followed by chemoradiation with or without lapatinib, a dual EGFR/ErbB2 kinase inhibitor, in patients with locally advanced resectable larynx and hypopharynx squamous cell carcinoma
European Organisation for Research and Treatment of Cancer0 sitesMarch 23, 2007
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- European Organisation for Research and Treatment of Cancer
- Status
- Active, not recruiting
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Histologically proven newly diagnosed laryngeal and hypopharyngeal
- •? Patients with T3 or T4 larynx or T2, T3 T4 hypopharynx
- •? Nodal status must be N0, N1, N2a, N2b, N2c and N3
- •? Patients must consent to access of their biological material for EGFR
- •status and must consent to PET
- •? Patient must have tumors amenable to surgery
- •? Absence of distant metastasis
- •? No prior treatment for head and neck cancer
- •? Age above 18
- •? WHO PS 0\-2
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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