Ultrasound Assessment of Gastric Volume in Elderly Patients Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Gastric volume 1
研究概览
简要总结
In the past, some guidelines advised no oral intake for at least 8 hours before any surgery, However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting.
The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited.
Some factors have been known to influence the gastric emptying rate, as for example, old age, pain, and the use of opioid analgesics.
In the previous study, evidence of increased pain was reported in patients undergoing staged bilateral total knee arthroplasty, in whom the second operated knee had greater sensitivity (tertiary hyperalgesia) due to the surgical injury to the first operated knee.
In the present study, the investigators will evaluate the effect of old age, surgical stress, pain, and the use of analgesics on the residual gastric volume in elderly patients undergoing staged-bilateral total knee arthroplasty.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 85 Years(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for staged bilateral total knee arthroplasty aged 65 to 85 years
- •American Society of Anesthesiologists physical status classification 1, 2, and 3
- •Body mass index < 35 kg/cm2
- •Patients administered carbohydrate-containing fluid 2 hours prior to surgery
排除标准
- •Previous surgery of the upper gastrointestinal tract
- •Achalasia
结局指标
主要结局
Gastric volume 1
时间窗: First stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
Gastric volume measured before induction of spinal anesthesia using ultrasound
Gastric volume 2
时间窗: Second stage operative, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes
Gastric volume measured before induction of spinal anesthesia using ultrasound
次要结局
未报告次要终点
研究者
Hyo-Seok Na
Professor
Seoul National University Bundang Hospital
