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临床试验/NCT04814706
NCT04814706已完成不适用

Ultrasound Assessment of Gastric Volume in Elderly Patients Undergoing Staged-bilateral Total Knee Arthroplasty After Drinking Carbohydrate-containing Fluids: A Prospective Observational Comparative Study

Seoul National University Bundang Hospital1 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2021年3月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
39
试验地点
1
主要终点
Gastric volume 1

研究概览

简要总结

In the past, some guidelines advised no oral intake for at least 8 hours before any surgery, However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting.

The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited.

Some factors have been known to influence the gastric emptying rate, as for example, old age, pain, and the use of opioid analgesics.

In the previous study, evidence of increased pain was reported in patients undergoing staged bilateral total knee arthroplasty, in whom the second operated knee had greater sensitivity (tertiary hyperalgesia) due to the surgical injury to the first operated knee.

In the present study, the investigators will evaluate the effect of old age, surgical stress, pain, and the use of analgesics on the residual gastric volume in elderly patients undergoing staged-bilateral total knee arthroplasty.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients scheduled for staged bilateral total knee arthroplasty aged 65 to 85 years
  • American Society of Anesthesiologists physical status classification 1, 2, and 3
  • Body mass index < 35 kg/cm2
  • Patients administered carbohydrate-containing fluid 2 hours prior to surgery

排除标准

  • Previous surgery of the upper gastrointestinal tract
  • Achalasia

结局指标

主要结局

Gastric volume 1

时间窗: First stage operation, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes

Gastric volume measured before induction of spinal anesthesia using ultrasound

Gastric volume 2

时间窗: Second stage operative, during the gastric volume measuring at preoperative holding area/ an average of 30 minutes

Gastric volume measured before induction of spinal anesthesia using ultrasound

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hyo-Seok Na

Professor

Seoul National University Bundang Hospital

研究点 (1)

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