IRCT20230111057113N2招募中2 期
Fertilization rate comparison in IntraCytoplasmic Sperm Injection(ICSI) cycles with second ejaculated sperm sample versus(Testicular sperm extraction) TESE sample in patients with high Deoxyribonucleic acid (DNA) fragmentation index(high DFI)
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 50 years（—）
- 性别
- All
入选标准
- •At least 1 failed ART(Assissted Reproductive technology) attempts
- •women between 18 and 40 years old
- •High DFI levels of more than 30% in semen samples at admission
- •Men between 20and 50 years old
排除标准
- •A male patient with obvious abnormalities noted in the medical history, physical examination, endocrine profile, and evidence of subclinical genital infections, leukocytospermia, cryptorchidism, cancer, history of chemotherapy or radiotherapy, or severe varicocele
- •2- Women with a history of poor response to ovarian stimulation or meeting the POSEIDON((Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) criteria for expected poor responders
- •Pre-implantation genetic screening (PGS), frozen/thawed embryo transfer cycles,
- •Apparent pathology of the uterus or tube
- •5- People with genetic disorders
- •6- Male patients with heavy smoking (more than 20 cigarettes per day)
- •7-Severe endometriosis
- •8-Patients with sperm freezing
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