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Clinical Trials/NCT06768554
NCT06768554
Active, not recruiting
Not Applicable

Retrospective Analysis of Prognostic Indicators of Diabetic Foot Ulcer

Shanghai Jiao Tong University School of Medicine1 site in 1 country2,000 target enrollmentOctober 31, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetic Foot Ulcer (DFU)
Sponsor
Shanghai Jiao Tong University School of Medicine
Enrollment
2000
Locations
1
Primary Endpoint
Ulcer healing rate in diabetic foot ulcers
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

The purpose of this study was to retrospectively analyze the wound condition, limb condition, ulcer recurrence and cardiovascular and mortality of patients with diabetic foot ulcer after admission to our hospital from 2009 to 2014, so as to understand the changes in the condition of patients with diabetic foot ulcer after treatment, provide evidence for the treatment of diabetic foot, and clarify the risk of diagnosis and treatment of diabetic foot.

Detailed Description

Diabetic foot ulcer (DFU) is one of the most common and serious complications in patients with diabetes. Due to its high incidence and complicated treatment process, DFU often has a significant impact on patients' quality of life. In order to gain an in-depth understanding of the wound changes of diabetic foot patients after admission, this study aims to systematically analyze the data of the database of diabetic foot patients in Ruijin Hospital, analyze the wound healing, ulcer recurrence and limb changes of diabetic foot patients, including amputation and other conditions, and then further determine the main factors affecting diabetic foot ulcer healing. Guide clinicians to develop more effective treatment plans; Provide data support to help optimize the treatment flow of diabetic foot and reduce length of stay and recurrence rates; To improve the overall treatment effect of diabetic foot patients and improve their quality of life. Objective: 1. The wound condition, limb condition, ulcer recurrence and cardiovascular and mortality changes of patients with diabetic foot after treatment were analyzed to clarify the risk of diagnosis and treatment of the disease and provide evidence for the treatment of diabetic foot. 2. To assess the progress of wound healing in patients with diabetic foot after admission to hospital and identify key factors that promote or delay healing. 3. By comparing the effects of different treatment methods (such as drug therapy, surgical intervention, adjuvant therapy, etc.), the most suitable treatment strategy is found. 4. The incidence of complications during and after treatment was analyzed, and effective management strategies were discussed. Methods:Through systematic analysis of the data from the database of diabetic foot patients in Ruijin Hospital, the wound healing, ulcer recurrence and limb changes of diabetic foot patients, including amputation, were analyzed, and then the main factors affecting diabetic foot ulcer healing were further determined.

Registry
clinicaltrials.gov
Start Date
October 31, 2024
End Date
October 30, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Shanghai Jiao Tong University School of Medicine
Responsible Party
Principal Investigator
Principal Investigator

Wang Weiqing

Professor

Ruijin Hospital

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years old
  • Gender: males and females
  • Patients diagnosed with diabetic foot ulcers (including those on the Wagner scale 0-5)
  • Receive inpatient treatment during the designated study period

Exclusion Criteria

  • Patients with severe systemic disease (such as end-stage renal disease, advanced cancer, etc.) may have influenced the study results
  • Patients unable to complete follow-up or with incomplete data

Outcomes

Primary Outcomes

Ulcer healing rate in diabetic foot ulcers

Time Frame: Look at the last 10 years retrospectively

Ulcer recurrence rate in diabetic foot ulcer patients

Time Frame: Look at the last 10 years retrospectively

Amputation rate in diabetic foot ulcers

Time Frame: Look at the last 10 years retrospectively

Mortality of diabetic foot ulcers

Time Frame: Look at the last 10 years retrospectively

Secondary Outcomes

  • Key independent factors that affect wound healing(Look at the last 10 years retrospectively)

Study Sites (1)

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