The Effect of Oral and Intravenous Ramosetron During Laparoscopic Cholecystectomy

Not Applicable

• Conditions: Nausea; Vomiting; Laparoscopic Cholecystectomy
• Interventions: Drug: intravenous ramosetron; Drug: oral ramosetron; Drug: oral and IV ramosetron

• Registration Number: NCT01041183
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Patients undergoing general anesthesia for laparoscopic cholecystectomy have a high risk of postoperative nausea and vomiting (PONV). The investigators investigated the effect of oral and IV ramosetron on PONV prophylaxis after laparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-11
• Study Start: 2009-11
• Primary Completion: 2009-12
• Study First Submitted: 2009-12-30
• Study First Submitted QC: 2009-12-30
• Last Update Submitted: 2009-12-30
• Study First Posted: 2009-12-31
• Last Update Posted: 2009-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• ASA I-II patients, 25-65 years, electivelaparoscopic cholecystectomy under general anesthesia

Exclusion Criteria

• GI disease, pregnant or menstruating, history of motion sickness and/or postoperative emesis, antiemetics within 24 h before surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group I	intravenous ramosetron	0.3 mg IV ramosetron
group II	oral ramosetron	0.1 mg oral ramosetron
group III	oral and IV ramosetron	0.1 mg oral ramosetron plus 0.3 mg IV ramosetron

Primary Outcome Measures

Name	Time	Method
Incidence of PONV	postoperative 0-48 h

Trial Locations

Locations (1)

Jung-Hee Ryu; 🇰🇷 Seongnam-si, Gyeonggi-do, Korea, Republic of