NCT01041183Unknown不适用
The Effect of Oral and Intravenous Ramosetron During Laparoscopic Cholecystectomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Incidence of PONV
研究概览
简要总结
Patients undergoing general anesthesia for laparoscopic cholecystectomy have a high risk of postoperative nausea and vomiting (PONV). The investigators investigated the effect of oral and IV ramosetron on PONV prophylaxis after laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-II patients, 25-65 years, electivelaparoscopic cholecystectomy under general anesthesia
排除标准
- •GI disease, pregnant or menstruating, history of motion sickness and/or postoperative emesis, antiemetics within 24 h before surgery
研究组 & 干预措施
group I
Active Comparator
0.3 mg IV ramosetron
干预措施: intravenous ramosetron (Drug)
group II
Active Comparator
0.1 mg oral ramosetron
干预措施: oral ramosetron (Drug)
group III
Active Comparator
0.1 mg oral ramosetron plus 0.3 mg IV ramosetron
干预措施: oral and IV ramosetron (Drug)
结局指标
主要结局
Incidence of PONV
时间窗: postoperative 0-48 h
次要结局
未报告次要终点
研究者
研究点 (1)
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