跳至主要内容
临床试验/CTRI/2026/03/105178
CTRI/2026/03/105178尚未招募不适用

A cross-sectional study to assess the cutaneous manifestations in patients with spinal abnormalities on magnetic resonance imaging : exploring the skin - spine axis

All India Institute of Medical Sciences Mangalagiri1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2026年3月12日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
150
试验地点
1
主要终点
Skin manifestations associated with spinal pathology

研究概览

简要总结

During development of organs, skin and the spine share a common embryological origin. There are multiple conditions of  nerve impingement such as notalgia  paresthetica , brachioradial pruritus in which patients can present with localized pruritus. Neuropathic itch is the sensation of pruritus resulting from neural dysfunction which can be localized or generalised. Compression of spinal cord can also present with neuropathic itch. This study aims to describe the skin changes seen in patients with magnetic resonance imaging (MRI) showing spinal abnormalities. Patients  who are meeting the inclusion criteria will be explained about the procedure and informed contest will be taken. Data will be collected according to case sheet and examination for skin changes and other findings will be done. The changes in skin and spinal abnormalities will be assessed in detail for their type, extent, severity, grading. Few patients who visit dermatology opd with potential neuropathic cutaneous changes will undergo MRI evaluation.  Data collected will be stored in password protected system and confidentiality will be maintained. The data will be statistically analysed

研究设计

研究类型
Observational

入排标准

年龄范围
12.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Patients consenting for the study Patients who have been diagnosed with spinal pathology having potential to cause neuropathic cutaneous changes or neuropathic itch on Magnetic resonance imaging Patients with skin conditions suggestive of neuropathic cutaneous changes and are undergoing MRI evaluation of spine.

排除标准

  • Pregnant and lactating women Contraindications for MRI.

结局指标

主要结局

Skin manifestations associated with spinal pathology

时间窗: Baseline

次要结局

  • Type & severity of spinal abnormalities, demographic data, association of severity between skin & spine abnormalities.(Baseline)

研究者

申办方类型
Research institution
责任方
Principal Investigator
主要研究者

Aisha P A

AIIMS, Mangalagiri

研究点 (1)

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