Lactated Ringer's and PlasmaLyte in Critically Ill Adults
试验速览
- 阶段
- 不适用
- 入组人数
- 12,000
- 试验地点
- 1
- 主要终点
- The incidence of acute kidney injury
研究概览
简要总结
In recent years, there has been a large amount of literature reports that normal saline can increase the incidence of renal injury in critically ill patients compared with balanced salt solution.However, no studies have compared the effects of different types of balanced salt solutions on the incidence of renal injury.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients admitted to ICU
排除标准
- •Patients <18 year old when admission
- •Patients who stay less than 24 hours in ICU
- •Patients who do not sufficient data for further analysis
- •Readmission patients during the study period
研究组 & 干预措施
Mix group
Patients who used two balanced salt solutions during icu stay
干预措施: RL (Drug)
Mix group
Patients who used two balanced salt solutions during icu stay
干预措施: PLA (Drug)
RL group
Patients who have only used lactated Ringer's during icu stay
干预措施: RL (Drug)
PLA group
Patients who have only used PlasmaLyte during icu stay
干预措施: PLA (Drug)
结局指标
主要结局
The incidence of acute kidney injury
时间窗: from admission to 28 days
The incidence of acute kidney injury
次要结局
- the incidency of CRRT events(from admission to 28 days)
- the ventilation free days(from admission to 28 days)
- the vasopressure free days(from admission to 28 days)
研究者
Kang Yan
Clinical Professor
West China Hospital