CTRI/2021/11/038112
Not yet recruiting
未知
Comparison of dose of Propofol when used in combination with ketamine versus Fentanyl for sedation and anti inflammatory effects in mechanically ventilated patients A double blind randomised controlled study
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: J952- Acute pulmonary insufficiency following nonthoracic surgeryHealth Condition 2: B968- Other specified bacterial agents as the cause of diseases classified elsewhereHealth Condition 3: I999- Unspecified disorder of circulatory system
- Sponsor
- AIIMS Jodhpur
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All ICU patients between 18 to 80 years who are expected to be on mechanical ventilation for more than 48 hours
Exclusion Criteria
- •1\) Patients weaned of mechanical ventilation within 48 hrs of mechanical ventilation
- •2\) Patients who are on non invasive mode of ventilation
- •3\) Patients who had cardiac arrest and received CPR within 48 hrs of mechanical ventilation
- •4\) Patients having history of dementia, Psychiatric disorder, on antipsychotic or antidepressants prior to ICU admission
- •5\) Pregnant females and patients having known hypersensitivity to any of the sedative agents
- •6\) Cardiogenic shock, Acute decompensated heart failure, MI
- •7\) Patients having end stage liver failure ( Child Pugh C)
- •8\) Primary neurological injury (TBI, Stroke, SCI, Anoxic brain injury, Brain edema)
- •9\) Hemodynamically unstable patients
Outcomes
Primary Outcomes
Not specified
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