Study on Lipid Profile Changes in Plasma and Intestinal Mucosa of Patients With Inflammatory Bowel Disease
Not yet recruiting
- Conditions
- Inflammatory Bowel Diseases
- Registration Number
- NCT06680076
- Lead Sponsor
- First Affiliated Hospital of Harbin Medical University
- Brief Summary
This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease.
- Detailed Description
This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease.
The investigators followed up with patients with different stages of IBD and collected plasma and lesion tissues from patients and healthy volunteers for lipid metabolism-related substances to assess the changes in lipid metabolism in patients with different stages of IBD and their impact on disease.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- Patients with inflammatory bowel disease; aged 18-80 years; all cases agreed to participate in the study.
- Healthy volunteers who agreed to participate in the study.
Exclusion Criteria
- Patients with severe heart disease; patients with severe kidney disease; patients with low blood pressure; patients with severe infections such as sepsis or pneumonia; patients who have used immunosuppressants such as 6-mercaptopurine, imidazole thiopurine, and cyclosporine within a short period, and women during pregnancy; patients who are post-colon resected; patients who disagreed to participate in the study.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differential lipid composition between disease and healthy groups 14 weeks Differences in lipid composition between disease and healthy groups.
Differences in lipid composition between active and remission disease 14 weeks Differences in lipid composition between active and remission disease
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Carol
🇨🇳Harbin, Heilongjiang, China