跳至主要内容
临床试验/CTRI/2025/07/091101
CTRI/2025/07/091101尚未招募2/3 期

A randomised controlled clinical trial to study the effect of Bhavprakashokta Panchakashay Yonivarti Dharan in Karnini Yonivyapada with special reference to cervical erosion.

Neha Hemant Phirke1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2025年7月30日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
76
试验地点
1
主要终点
To evaluate effect of bhavprakashokta panchakashay yonivarti dharan in karnini yonivyapad

研究概览

简要总结

Normal vaginal secretions consist of white coagulated material involving doderlein’s bacilli, squamous cells and coagulated secretions. The vaginal contents are mostly derived from squamous cells of the vaginal mucosa. Some, from endometrial and cervical

secretions. Pathological conditions such as cervical erosion causes increased mucus secretion and patient complaints of mucous discharge at vaginal orifice. In leucorrhoea, the normal vaginal secretions are increased in amount. In such

patients there will be no excess of leucocytes present, and discharge is non purulent. Purulent discharges are due to specific infections such as tricomoniasis, moniliasis and

gonorrhoea. Ulcerated growths of cervix and discharges caused by urinary fistula are of different type and are excluded from term “leucorrhoea”. Increases in normal vaginal

secretions is physiological in pregnancy, puberty, and premenstrual phase of menstrual cycle. Non-pathogenic leucorrhoea can be classified into 1) cervical and 2) vaginal.

Discharge from endocervical glands increases in conditions such as chronic cervicitis, cervical erosion, mucous polypi, and ectropion.

Cervical erosion is benign condition if left untreated may lead to infertility and cervical malignancy.

Cervical erosion resembles to karnini yonivyapada according to ayurvedic texts. In ayurvedic classics it is mentioned that non-purulent vaginal discharge is caused due to consumption of kaphakara aahara and vihara.

Hence kaphashamaka treatment is needed to subside the symptom. According to aacharya charak and vagbhatta, vata-kapha

doshas are involved in karnini yonivyapada whereas according to aacharya sushruta, only kapha dosha along with rakt is involved and other kaphaj features like unctuousness, itching, etc are seen.

In following study, one attempt will be made by using a formulation

(panchakashaya) described by Bhavaprakasha for symptom Yonipichilta in karnini Yonivyapad, to rule out its effect by using its choorna’s yonivarti.

研究设计

研究类型
Interventional
分配方式
Other
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
Female

入选标准

  • Married female patients Diagnosed and confirmed patient of cervical erosion having nonpurulent vaginal discharge.

排除标准

  • Benign or malignant lesion of cervix Patient having uterine prolapse Hysterectomy patients Early menopausal women Pregnant women HIV VDRL HBSAG positive patients.

结局指标

主要结局

To evaluate effect of bhavprakashokta panchakashay yonivarti dharan in karnini yonivyapad

时间窗: 6 days

次要结局

  • To study the literature of karnini yonivyapad w.s.r. to cervical erosion in details by ayurvedic and modern perspective.(To study litrature of bhavprakashokta panchakashay gan.)

研究者

发起方
Neha Hemant Phirke
申办方类型
Other [Self ]
责任方
Principal Investigator
主要研究者

Dr Neha Hemant Phirke

Yashwantrao Chavan Ayurvedic Medical College and Hospital

研究点 (1)

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