Inspiratory and Expiratory Muscle Training in Critically Ill Patients Weaned From Mechanical Ventilation

University of Liege1 site in 1 country100 target enrollmentOctober 1, 2020

ConditionsCritical Illness Inspiratory Muscle Strength Mechanical Ventilation Respiratory Muscle Training

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Critical Illness
Sponsor: University of Liege
Enrollment: 100
Locations: 1
Primary Endpoint: change in inspiratory muscle strength
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Respiratory muscle weakness is common after mechanical ventilation and occurs early. This can limit functional recovery. Respiratory muscle training is often neglected in clinical practice. Some data indicates that inspiratory muscle training increases inspiratory muscle strength and quality of life. The aim of the study is to assess the impact of combined inspiratory and expiratory muscle training on inspiratory muscle strength. The second aim is to assess the impact of this training program on expiratory muscle strength.

Registry

clinicaltrials.gov

Start Date

October 1, 2020

End Date

September 1, 2023

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

Male

Investigators

Sponsor

University of Liege

Responsible Party

Principal Investigator

Rousseau

Head of clinic

University of Liege

Eligibility Criteria

Inclusion Criteria

•patient from mechanical ventilation after at least 24 hours of support
•collaborative patient

Exclusion Criteria

•confusion, mental disorder
•not french speaking
•pulmonary surgery in the past 12 months
•external ventricular drain
•previous pneumothorax or pneumothorax not drained
•rib fractures
•alveolar hemorrhage
•hemodynamic instability
•labial occlusion impossible (face burn, facial paralysis)
•patient refusal

Outcomes

Primary Outcomes

change in inspiratory muscle strength

Time Frame: 1 month after ICU discharge (compared to ICU discharge)

measurement of maximal inspiratory pressure

Secondary Outcomes

change in expiratory muscle strength(1 month after ICU discharge (compared to ICU discharge))
respiratory infections(1 month after ICU discharge)
change in dyspnea perception(1 month after ICU discharge (compared to hospital discharge))
impact of dyspnea on physical activities(1 month after ICU discharge)