Inspiratory and Expiratory Muscle Training in Critically Ill Patients Weaned From Mechanical Ventilation
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- change in inspiratory muscle strength
研究概览
简要总结
Respiratory muscle weakness is common after mechanical ventilation and occurs early. This can limit functional recovery. Respiratory muscle training is often neglected in clinical practice. Some data indicates that inspiratory muscle training increases inspiratory muscle strength and quality of life. The aim of the study is to assess the impact of combined inspiratory and expiratory muscle training on inspiratory muscle strength. The second aim is to assess the impact of this training program on expiratory muscle strength.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
盲法说明
patients are masked: they will all benefit from respiratory physiotherapy, with placebo or real muscle training investigator and care providers are unmasked, as they set the training parameters
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •patient from mechanical ventilation after at least 24 hours of support
- •collaborative patient
排除标准
- •confusion, mental disorder
- •not french speaking
- •pulmonary surgery in the past 12 months
- •external ventricular drain
- •previous pneumothorax or pneumothorax not drained
- •rib fractures
- •alveolar hemorrhage
- •hemodynamic instability
- •labial occlusion impossible (face burn, facial paralysis)
- •patient refusal
结局指标
主要结局
change in inspiratory muscle strength
时间窗: 1 month after ICU discharge (compared to ICU discharge)
measurement of maximal inspiratory pressure
次要结局
- change in expiratory muscle strength(1 month after ICU discharge (compared to ICU discharge))
- respiratory infections(1 month after ICU discharge)
- change in dyspnea perception(1 month after ICU discharge (compared to hospital discharge))
- impact of dyspnea on physical activities(1 month after ICU discharge)
研究者
Rousseau
Head of clinic
University of Liege