Prevention of Potentially Inappropriate Prescribing in Late Life Using STOPP (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions) and START (Screening Tool to Alert Doctors to Right i.e. Appropriate Indicated Treatment): A Randomized Controlled Trial.
试验速览
- 阶段
- 4 期
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Appropriateness of prescribing using the Medication Appropriateness Index and the Assessment of Underutilization of Medication Tool
研究概览
简要总结
Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug events and hospitalization.
STOPP (Screening Tool of Older Person's potentially inappropriate Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) is a new screening tool designed to detect instances of potentially inappropriate medication use and under-prescribing of clinically indicated medications in older patients. The purpose of this study is to determine whether clinical implementation of STOPP/START criteria in hospitalized older patients is effective in improving prescribing quality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients aged 65 years and older admitted to the general medical services of Cork University Hospital, Cork, Ireland
排除标准
- •Patient admitted to a geriatric medicine service, psychiatry of old age service or clinical pharmacology service, or under review of these services during the previous 12 months
- •Critically ill patient (admitted to the intensive care unit)
- •Terminally ill patient
- •Refusal of patient or hospital physician to participate
- •No time for the research physician to enrol the patient within 3 days of admission
结局指标
主要结局
Appropriateness of prescribing using the Medication Appropriateness Index and the Assessment of Underutilization of Medication Tool
时间窗: Measured on admission, discharge and at 2, 4 and 6 months post-discharge
次要结局
- Composite health resource utilization including hospital readmission and primary care consultations(at 2, 4 and 6 months post-discharge)