Sudden cardiac death in kidney disease

Not Applicable

• Conditions: End-stage kidney disease stage IV and V; Urological and Genital Diseases; Chronic kidney disease

• Registration Number: ISRCTN10855079
• Lead Sponsor: Päijät-Hämeen Keskussairaala

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-26
• Last Update Posted: 14 April 2020
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Stage 4 (pre-dialysis, glomerular filtration rate 15-29 mL/min/1.73m²) or stage 5 (end-stage renal disease, <15 mL/min/1.73m² or dialysis)
2. Planned active treatment is either hemodialysis or peritoneal dialysis, or kidney transplantation. The hemodialysis also includes short daily home hemodialysis

Exclusion Criteria

1. Age >75 years
2. Age <18 years
3. Presence of a non-cardiovascular and non-renal disease which limits the expected life-span to less than 1 year
4. Probable noncompliance

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence and burden of atrial fibrillation, atrial flutter, bradycardia, sustained and non-sustained ventricular tachycardia, ventricular premature contractions, asystole and ventricular fibrillation are quantified using the data from insertable cardiac monitors over the course of the follow-up time of 3 years

Secondary Outcome Measures

Name	Time	Method
<br> 1. Temporal association between dialysis and the arrhythmias using the data from insertable cardiac monitors over the course of the follow-up time of 3 years<br> 2. Prevalence of arrhythmias using the data from insertable cardiac monitors over the course of the follow-up time of 3 years.<br> 3. Survival at 3 years measured using patient records.<br>