Ocular Findings in Women With Primary Antiphospholipid Syndrome and Their Association to Bad Obstetric Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The incidence of Ocular changes in females with antiphospholipid syndrome
研究概览
简要总结
Antiphospholipid antibody syndrome (APS) is an autoimmune disease characterized by systemic thrombosis and bad obstetric history. APS secondary to another medical disorder is the most common. Visual and ocular changes e.g. vaso-occlusive disease of retinal and choroidal vessels are found in patients with secondary APS. Patients with primary APS have also been reported to have ocular changes e.g. retinal vascular occlusion
The aim of our study to detect prevalence of ocular changes in women diagnosed with primary APS and correlation of these changes with adverse obstetric outcome. If a correlation is present, ocular findings in women with APS could be used in the future as a predictor for poor obstetric outcome.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age: 18 to 35 years
- •Females with primary antiphospholipid syndrome
排除标准
- •Age: below 18 years and above 35 years
- •Auto-immune diseases e.g. SLE and other connective tissue disease
- •Medical diseases causing retinal vascular changes e.g. hypertension, diabetes mellitus, sickle cell anemia.
- •Previous vitreo-retinal surgery
结局指标
主要结局
The incidence of Ocular changes in females with antiphospholipid syndrome
时间窗: On the same day of enrollment into the study
Number of participants with ocular findings detected by ophthalmological examination
次要结局
未报告次要终点
研究者
Ahmed AA Wali, MD
Lecturer of Obstetrics and Gynecology
Cairo University