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Clinical Trials/NCT04379206
NCT04379206
Completed
Not Applicable

Social Network Approach for Increasing Testing Coverage Among Men Who Have Sex With Men

Chinese University of Hong Kong1 site in 1 country463 target enrollmentMarch 1, 2021
ConditionsHIV Infections

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV Infections
Sponsor
Chinese University of Hong Kong
Enrollment
463
Locations
1
Primary Endpoint
effectiveness of the approach in reaching MSM who have never or not recently tested for HIV
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

HIV testing is essential in shortening the time to identify a new infection, the first 90 of the UNAIDS 90-90-90 targets. However, over one-third of the men who have sex with men (MSM) had never been tested for HIV; even if they did, one-fifth had their tests done more than a year ago. Assortative mixing pattern observed in the HIV-positive MSM group shaped the transmission dynamics and could be leveraged for intervention. Barriers to access HIV testing services could, on the other hand, be hurdled by self-tests. A network approach for intervention could therefore be promising in delivering effective HIV self-tests. To experiment with such an approach, a 2-phase study was conceptualised incorporating actual network-based referred HIV self-tests and an agent-based simulation evaluating its impact. Sixty-four MSM would be recruited as seeds for promoting HIV self-tests within their network and those being referred could refer their friends for the same after passing online training. To facilitate the process, an online platform would be developed offering information, collecting informed consent, requesting HIV self-test kits, returning results, performing online training, and referring peers. Participants could opt to receive self-tests by delivery or to conduct it on-site with staff assistance. A hotline with video conferencing support would be maintained to assist those who self-test at home. They could also choose between blood and oral fluid tests. Two user interfaces, namely gamification and neumorphism, would be randomly assigned. Primary outcomes to measure are number and proportion of MSM who had never or not tested within 12 months and the associating factors, and usability of the two user interfaces. Data collected in the empirical study would be used for parameterising the agent-based simulation to evaluate the impact of the approach in increasing testing coverage and shortening time to diagnosis. Its economic assessment would also be performed to cost each new infection to be identified. The approach could be feasible and effective to be adopted for future broader implementation for peer-led HIV self-test kit or HIV prevention message distribution.

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
May 12, 2021
Last Updated
4 years ago
Study Type
Observational
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tsz Ho Kwan

Postdoctoral Fellow

Chinese University of Hong Kong

Eligibility Criteria

Inclusion Criteria

  • had sex with another male in the preceding year
  • able to communicate in written Chinese or English
  • normally resided in Hong Kong

Exclusion Criteria

  • prisoners
  • having mental illnesses that informed consent cannot be obtained

Outcomes

Primary Outcomes

effectiveness of the approach in reaching MSM who have never or not recently tested for HIV

Time Frame: Through study completion, at year 2

proportion of testers who have never or not recently tested for HIV

Usability and acceptability of two user interfaces

Time Frame: Through study completion, at year 2

System Usability Scores (SUS) and proportion of testers giving a score of at least 71

Secondary Outcomes

  • Proportion and characteristics of promoters(Through study completion, at year 2)
  • Preference of two forms of HIV self-testing(Through study completion, at year 2)
  • Effect of network-based HIV self-test promotion in controlling transmission among MSM(Through study completion, at year 2)
  • Determinants of key actors in the social network(Through study completion, at year 2)

Study Sites (1)

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