Efficacy of clotrimazole 1 % and miconazole1% in otomycosis.
Not Applicable
Completed
- Conditions
- otomycosis.Otitis externa in mycoses
- Registration Number
- IRCT201502241138N15
- Lead Sponsor
- Guilan University of Medical Science, Vice Chancellor for Resarch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
Inclusion: All patients who visit in Amir-Al.. and have a clinical diagnosis for otomycosis. Exclusion: Otitis externa along with external ear canal stenosis;a history of ear surgery; diabetes mellitus; immunocompromise ; chronic discharging ear
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fungal otitis externa. Timepoint: Weekly up to 2 week and at the end of 4th week. Method of measurement: Clinical examination.
- Secondary Outcome Measures
Name Time Method The patient's response to creams. Timepoint: Weekly up to 2 week and at the end of 4th week. Method of measurement: Clinical examination.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the antifungal activity of clotrimazole and miconazole in otomycosis?
How does the efficacy of 1% clotrimazole cream compare to standard-of-care treatments for fungal otitis externa?
Are there specific biomarkers that correlate with treatment response to azole antifungals in otomycosis patients?
What are the potential adverse events associated with topical azole therapies for otomycosis and how are they managed?
What combination antifungal approaches show promise in treating drug-resistant otomycosis compared to monotherapy with clotrimazole or miconazole?