Exploring physiological and metabolomic changes with sauna and exercise in healthy young volunteers

Not Applicable

• Conditions: cardiovascular disease prevention; peripheral arterial disease prevention; environmental toxin metabolism; wellness; Alternative and Complementary Medicine - Other alternative and complementary medicine; Cardiovascular - Normal development and function of the cardiovascular system; Metabolic and Endocrine - Normal metabolism and endocrine development and function

• Registration Number: ACTRN12618000679280
• Lead Sponsor: RMIT University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-26
• Last Update Posted: 26 November 2018

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

All participants will be
-aged between 18-40 years
-non-smokers
-English speaking and able to give written informed consent
-willing and able to engage in sauna activities (both far-infrared and Finnish-style)
-willing and able to engage in 30 minutes of moderate-intensity exercise (stationary bicycle)
-willing to avoid over the counter medicines such as Nurofen and Paracetamol for 24 hours prior to the study sessions.
-willing to avoid topical perfume and skin preparations for 24 hours prior to the study sessions
-willing to fast overnight (minimum 12 hours)

Exclusion Criteria

Participants will be excluded if they are:
- smokers
- diagnosed with diabetes or chronic medical condition (i.e. current or previous history of renal, cardiac, gastrointestinal, liver, skin, psychiatric disorders or respiratory -other than asthma not requiring continuous medication) or any other condition for which the subject is currently taking medications or in the opinion of the investigators would impede competence, compliance, or participation in the study.
-recent hospitalisation, surgery or antibiotic therapy
-taking any medications or supplements on a regular basis; regular consumption of prescription or OTC (over the counter) medications such as proton pump inhibitors, non-steroidal anti-inflammatory drugs, or pain medications
-clinically underweight (BMI < 18.5 kg/m2) or obese (BMI > 30 kg/m2);
-orthopaedic or cardiovascular limitations that precludes participation in sauna or moderate exercise;
-regular performance of > 60 minutes daily, 7 days/week of continuous physical activity defined as vigorous” by Sports Medicine Australia (i.e. training for triathlon, marathon)
-any participation in regular heat-acclimation (i.e. hot yoga) or exercise-acclimation activities (i.e. hyperbaric chamber) within the past 6 months.
-have been regularly sauna bathing during the past 6 months
-pregnant or expect/attempting to become pregnant or impregnate
-currently having irregular menstrual periods
-unable to give informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified