Diffusion-weighted magnetic resonance imaging (DW-MRI) as an imaging biomarker: reproducibility of measurements in liver and lung.
Completed
- Conditions
- Metastasisneoplasma10027476
- Registration Number
- NL-OMON39706
- Lead Sponsor
- niversitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 14
Inclusion Criteria
Volunteer study
* Age 30-50 or 60-80 years
* Able to remain supine for 30 minutes in the scanner
* Written informed consent
Patient study
* Age 18 years or older
* Colorectal liver metastases or lung metastases, or primary lung cancer (histological confirmation only in uncertain metastatic deposits)
* Minimum of one lesion > 2cm in diameter in liver or lung respectively
* Able to remain supine for 30 minutes in the scanner
* Written informed consent
Exclusion Criteria
* Contraindications for MRI
* Antitumor treatment targeted on the evaluable liver metastasis
* Antitumor treatment targeted less than 1 week prior to scan in malignant lung lesions
* Claustrophobia
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Reproducibility of apparent diffusion coefficient (ADC) measured with DW-MRI.</p><br>
- Secondary Outcome Measures
Name Time Method <p>n/a</p><br>