Pilot trial of Aspirin versus Ticagrelor in Congestive Heart Failure

Phase 2

Withdrawn

• Conditions: Congestive Heart failure patients; Heart Failure; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12613000826741
• Lead Sponsor: St Vincent's Hospital, Heart Failure Research Trust Fund #869883

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-26
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Men or women age greater than 18 years of age
-on aspirin and ACE inhibitor
-symptomatic heart failure with stable therapy
-Serum pro-BNP greater than 600 pg/mLor NT pro BNP greater than 400 pg/mL and Heart Failure
-ongoing treatment with diuretics
-informed consent

Exclusion Criteria

-aspirin contraindicated or ticagrelor
-Heart failure due to a reversible cause
-ongoing indication to continue aspirin or other antiplatelet therapy
-Atrial fibrillation
-Unstable heart failure or treatment regime
-life limiting systemic illness
-conditions that might interfere with protocol compliance]
-Patients taking NSAID's, clopidogrel, Prasugrel, cyclosporin, or simvastin and ongoing CYP3A4 inhibitors

Study & Design

• Study Type: Interventional
• Study Design: Not specified