Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics
- Conditions
- FrailtySarcopenia
- Registration Number
- NCT02073370
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults are still under-clarified and need for further study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 350
Inclusion Criteria
- functional decline in recent one year
- cognitive impairment
- depressive symptom
- mobility impairment
- fall in recent one year
- eating or feeding problems
- weight loss
- co-morbid conditions≧5
- tracking by different physician ≧3 in recent half year
- poly-pharmacy≧8 in recent 3 months
- hospitalization ≧1 in recent one year
- emergency visits≧2 in recent one year
- aged ≧ 80.
Exclusion Criteria
- non-ambulatory (bed-ridden) patients
- long-term residents at nursing homes
- patients with a life expectancy shorter than six months
- impairment in vision, hearing, or communicative ability, making convenience of clinical evaluation during the study period impossible.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Domestic operation tool of sarcopenia for older adults Baseline Young health adults are recruited for measurement of body composition using bio impedance analysis in order to establish the norm of skeletal muscle index
- Secondary Outcome Measures
Name Time Method Change from baseline in body composition during aging up to 2 years Using anthropometric measurements, and bio impedance analysis, the change in body composition are measured in the recruited older adults
Trial Locations
- Locations (1)
National Taiwan University Hospital
🇨🇳Taipei, Taiwan