NCT02073370Unknown不适用
Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Domestic operation tool of sarcopenia for older adults
研究概览
简要总结
Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults are still under-clarified and need for further study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •functional decline in recent one year
- •cognitive impairment
- •depressive symptom
- •mobility impairment
- •fall in recent one year
- •eating or feeding problems
- •weight loss
- •co-morbid conditions≧5
- •tracking by different physician ≧3 in recent half year
- •poly-pharmacy≧8 in recent 3 months
- •hospitalization ≧1 in recent one year
- •emergency visits≧2 in recent one year
- •aged ≧ 80.
排除标准
- •non-ambulatory (bed-ridden) patients
- •long-term residents at nursing homes
- •patients with a life expectancy shorter than six months
- •impairment in vision, hearing, or communicative ability, making convenience of clinical evaluation during the study period impossible.
结局指标
主要结局
Domestic operation tool of sarcopenia for older adults
时间窗: Baseline
Young health adults are recruited for measurement of body composition using bio impedance analysis in order to establish the norm of skeletal muscle index
次要结局
- Change from baseline in body composition during aging(up to 2 years)
研究者
研究点 (1)
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