Effect of acupuncture on pain and inflammatory mediators in patients with fibromyalgia

Not Applicable

Recruiting

• Conditions: Fibromyalgia; Women; C05.651.324; M01.975

• Registration Number: RBR-6hvjnq
• Lead Sponsor: niversidade Federal de Santa Maria/Pro-Reitoria de Pós-Graduação

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women;
Age between 20 and 60 years old;
Diagnosis of fibromyalgia according to the American College of Rheumatology criteria.

Exclusion Criteria

Severe psychiatric illness;
With neurological or sensory deficit;
Patients who have contraindications to acupuncture;
Pregnant women;
Lactating;
Patients unable to attend the acupuncture sessions;
Patients who do not accept the conditions proposed in the term of free and informed consent.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in pain level determined by Visual Analogue Scale (VAS) and algometry (Force Dial FDK / FDN Series, Wagner Instruments, Greenwich - USA) before and after treatment. The algometer records the pain in kilograms (kg) borne by the individual in 8 points located, bilaterally, in the suboccipital region, trapezial muscle, second rib and lateral epicondyle

Secondary Outcome Measures

Name	Time	Method
Improvement in Quality of Life determined by the reduction in the Fibromyalgia Impact Questionnaire (FFI) score before and after intervention;Increased levels of anti-inflammatory interleukins (interleukin-10 (IL-10) and interleukin-4 (IL-4)) and reduced levels of proinflammatory interleukins (interleukin-6 (IL-6), Tumor Necrosis Factor -alpha (TNF-alpha)) Measured on a flow cytometer before and after intervention