Combined Amniotic Membrane and Platelet Rich Plasma Clot for Management of Central Corneal Perforation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Closure of the corneal wound
研究概览
简要总结
Use of amniotic membrane(AMT) and platelet rich plasma (PRP) clot for closure of central corneal perforation
详细描述
Use of amniotic membrane and platelet rich plasma clot for closure of central corneal perforation either post infective or posttraumatic
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •central corneal perforation
排除标准
- •active infection
- •posterior segment pathology
- •non seeing eye
研究组 & 干预措施
Corneal perforation patients
Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention.
Patients will undergo:
Platelet rich plasma clot implantation Wound closure with amniotic membrane
干预措施: Platelet rich plasma clot implantation (Procedure)
Corneal perforation patients
Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention.
Patients will undergo:
Platelet rich plasma clot implantation Wound closure with amniotic membrane
干预措施: Wound closure with amniotic membrane (Procedure)
结局指标
主要结局
Closure of the corneal wound
时间窗: 3 months
sealing of the edges corneal gap, with formation of scar tissue
次要结局
未报告次要终点
研究者
Ahemd Abdelghany
Lecturer of Ophthalmology, Faculty of Medicine
Minia University