Evaluation of esCCO monitoring for continuous, non-invasive measurement of cardiac output - COKA

This study evaluated the validity of the non-invasive esCCO monitoring for the assessment of CO and SV as well as their indices in pregnant patients undergoing minimally-invasive foetoscopic surgery for spina bifida. As such, a healthy and homogenous cohort of pregnant patients who underwent minimally-invasive foetoscopic surgery for spina bifida of their unborn child was investigated. Our study found that esCCO-derived parameters did not correlate with the results of the pulse contour analysis. Only COesCCO showed a weak correlation with COTPTD. Analogous results were found in a subanalysis investigating the influence of PACI on the performance of esCCO. Overall, esCCO underestimated CO, CI, SV, and SVI consistently. Supposing a tolerance of 10% deviation to the established TPTD, esCCO failed to achieve reliable results.