Evaluation of esCCO monitoring for continuous, non-invasive measurement of cardiac output
- Conditions
- Q05.9I50.9Spina bifida, unspecifiedHeart failure, unspecified
- Registration Number
- DRKS00008769
- Lead Sponsor
- niversitätsklinikum GießenAbteilung für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie
- Brief Summary
This study evaluated the validity of the non-invasive esCCO monitoring for the assessment of CO and SV as well as their indices in pregnant patients undergoing minimally-invasive foetoscopic surgery for spina bifida. As such, a healthy and homogenous cohort of pregnant patients who underwent minimally-invasive foetoscopic surgery for spina bifida of their unborn child was investigated. Our study found that esCCO-derived parameters did not correlate with the results of the pulse contour analysis. Only COesCCO showed a weak correlation with COTPTD. Analogous results were found in a subanalysis investigating the influence of PACI on the performance of esCCO. Overall, esCCO underestimated CO, CI, SV, and SVI consistently. Supposing a tolerance of 10% deviation to the established TPTD, esCCO failed to achieve reliable results.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 35
gynecological patients; pregnant women with the indication for a fetoscopic procedure
Age <18 years, atrial fibrillation, pacemaker
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of cardiac output measured with the esCCO system compared to measurement with the PiCCO system perioperatively (every 30 minutes until the end of the operation)
- Secondary Outcome Measures
Name Time Method Comparison of heartbeat volume, systemic resistance and possible influencing factors (age, gender, previous illnesses, catecholamine therapy, storage, fluid therapy, respiration) when measuring with the esCCO system versus measurement with the PiCCO system