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Clinical Trials/NCT04702165
NCT04702165
Completed
Phase 1

Image - Navigated Resection of Lung Nodules

Navigation Sciences, Inc.1 site in 1 country25 target enrollmentJune 3, 2021
ConditionsLung Diseases

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Lung Diseases
Sponsor
Navigation Sciences, Inc.
Enrollment
25
Locations
1
Primary Endpoint
To compare the measurements from the J-bar fiducial to the first staple line obtained by the device in vivo to that performed in the frozen section room on the lung specimen obtained (which includes both the J bar and the staple line).
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

This is an open label study lung nodules that are either cancer or non-cancer and who are eligible for surgical resection. Patients will undergo their surgery with the help of the Lung Resection Marker Locator Kit which will assist the surgeon in both the location and resection of the lung nodule under real-time guidance.

Registry
clinicaltrials.gov
Start Date
June 3, 2021
End Date
June 16, 2022
Last Updated
9 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Males or females aged 21 years or older as it is extremely rare for younger people to be at risk for lung cancers.
  • Be deemed candidates for the lung resection surgery, which will be determined by their treating Thoracic Surgeon (also a physician investigator)
  • Have lesions that are nodules/GGO or other abnormal opacity that can be accurately measured in at least one dimension using conventional techniques
  • Seen at BWH Thoracic Surgery outpatient clinics or as inpatient (Note: Subjects will be formally consented to the study at BWH only)

Exclusion Criteria

  • Female subjects pregnant or breastfeeding
  • Subjects with a pacemaker or equivalent devices (AICD) due to the use of electromagnetic tracking generator.
  • Patients who are not scheduled for lung surgery

Outcomes

Primary Outcomes

To compare the measurements from the J-bar fiducial to the first staple line obtained by the device in vivo to that performed in the frozen section room on the lung specimen obtained (which includes both the J bar and the staple line).

Time Frame: 1 day

device feasibility

Secondary Outcomes

  • demonstrate safe surgical remove of lung nodule(30 day)
  • time required for device placement(1 day)
  • whether coefficient is needed(1 day)

Study Sites (1)

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