Effect of fluoxetine on clinical symptoms and echocardiographic findings in patients with mitral valve prolapse and generalized anxiety disorder.

Not Applicable

• Conditions: Condition 1: Generalized anxiety disorder. Condition 2: mitral valve prolapse.; Generalized anxiety disorder; Mitral (valve) prolapse

• Registration Number: IRCT2014102819721N1
• Lead Sponsor: Sabzevar University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients who their mitral valve prolapse (MVP) is confirmed by echocardiography and have clinical symptoms of MVP (at least must have palpitation or chest pain).Exclusion criteria: medical conditions which directly or indirectly can induce anxiety including anemia;hypercalemia;hypoglycemia;drugs or alcohol withdrawal syndrome;vertigo;thyrotoxicosis;hypercapnea;hyponatremia;central nervous system disorders such as seizures;asthma;ischemic heart disease;malignancies;drugs such as anticonvulsants;antimicrobials;broncho dilators;digitalis;estrogen;insulin;nonsteroidal anti-inflammatory drugs;antidepressants;antihistamines;calcium channel blockers;dopamine;inotropics;levodopa;thyroxine;corticosteroids;smoking;patients who dont full fill DSM-IV criteria and are not included in generalized anxiety disorder category;any other documented psychological problems;patients who are not interested in continuing medications and are willing to be excluded;patients who do not take their medications regularly;patients who are prescribed with other drugs during the study;patients who are not capable to continue study because of drug adverse effects or need to change their drugs according to physicians order.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain severity. Timepoint: Every week. Method of measurement: Base on 11 point likert scale.;Echocardiographic changes. Timepoint: At the begining and the end of study. Method of measurement: By use of transthoracic echocardiography.;Palpitation. Timepoint: Every week. Method of measurement: Base on 11 point likert scale.