Accuracy in Resection of Non-pedunculated Colonic Lesions 5-20 mm With/Without Using NBI
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 113
- 试验地点
- 2
- 主要终点
- NBI efficacy in predicting radicality of polypectomy by taking random biopsies of margins after resection of the lesion
研究概览
简要总结
Interval colon cancers are an important clinical issue. A recent paper from Pohl et al focused on non-pedunculated polyps of 5-20 mm, evaluating non complete polypectomy revealing that 10% of these polyps were not completely resected. This fact was attributed to size and histology. In this study the investigators want to evaluate the radical resection of non-pedunculated polyps of 5-20 mm by performing biopsies on the margins immediately after polypectomy, to establish if the use of Narrow Band Imaging (NBI) could be useful in the definition of the margins of the lesion before polypectomy.
详细描述
Interval colon cancers are an important clinical issue. Literature dealing with technics and quality of polypectomy is scarce. A recent paper from Pohl et al focused on non-pedunculated polyps of 5-20 mm, evaluating non complete polypectomy and factors related to it, revealing that 10% of these polyps were not completely resected. This fact was attributed to size and histology (the majority of non completely resected ones, were polyps of 10-20 mm and with serrated characteristics at the histology). In this study the investigators want to evaluate the radical resection of non-pedunculated polyps of 5-20 mm by performing biopsies on the margins immediately after polypectomy, to establish if the use of Narrow Band Imaging (NBI) could be useful in the definition of the margins of the lesion before polypectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Every polyp ≥ 5 mm and ≤ 20 mm
排除标准
- •Inflammatory bowel Disease and/or International Normalized Ratio > 1.5
结局指标
主要结局
NBI efficacy in predicting radicality of polypectomy by taking random biopsies of margins after resection of the lesion
时间窗: 12 months
次要结局
未报告次要终点
研究者
Alida Andrealli
MD
Valduce Hospital
